Textbook in PDF format

This book is dedicated to the discussion of several biomedical applications of the mechanical phenotyping of cells and tissues to specific disease models. The topical chapters on mechanics in disease are preceded by chapters describing cell and tissue structure and their relationship with the biomechanical properties, as well as by the description of dedicated sample preparation methods for the nano- and microscale mechanical measurements.
Introduces the basics of physics and biology of the cell before delving into the mechanics of diseases. With detailed explanation of sample preparation and characterization techniques. Plenty of real-life examples, from heart infarction to cancer.
Preface
Acknowledgment
Table of Contents of Volume 2 – Biomedical Applications
Table of Contents Volume 1 – Biomedical Methods
Contributing Authors
Cell and Tissue Structure
Cell Structure: An Overview
The Cytoskeleton
Cell Membrane and Glycocalyx
Functions of Plant Cell Walls in Root Growth and Environmental Interactions
Extracellular Matrix
Mechanotransduction
Sample Preparation
Cell Culture
Tissue Preparation
Soft Hydrogels Mimicking the Extracellular Matrix
Preparation and Deposition of Plant Roots for AFM Nanomechanical Measurements
Mechanics in Diseased Cells and Tissues
Cardiovascular Diseases
Respiratory Diseases
Cancer
Blood Cells
Diabetes and Endothelial Nanomechanics
Chronic Liver Diseases
Mechanics of Dupuytren’s Disease
Intermediate Filaments
Laminopathies
Integrative Approaches Using AFM to Study Pathogenic Bacteria and Infection
Stiffening of the Plant Root Cell Wall Induced by a Metallic Stress
Outlook
Mechanics of Diseases: An Outlook
Subject Index (Volume 1 & Volume 2)