Bagasra O. Forensic DNA Analyses Made Simple. A Guide for the Curious 2023
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Textbook in PDF format Sequencing genetic material is now common practice. The general population have become consumers of this information but without an understanding of the biological processes that render sequencing data useful. The interpretation of genetic sequence depends on an appreciation of the basics of genetics and the limits of such data. This book provides the background necessary to understand, interpret, and apply sequencing information to real- world problems. Replication of genetic material, the structure of DNA, typing methods, and forensic applications are all discussed in this useful primer. Introduction The Cell How Cells Divide and Why It Is Important to Know the Process Structure of DNA and Why We Use DNA in Forensic Science: What Are Small Tandem Repeats (STRs), and Why Do We Use Them? Capillary Gel Electrophoresis to Analyze DNA in a Crime Lab Sex Determination by STR The Combined DNA Index System (CODIS) How STRs Are Analyzed in a Forensic Laboratory Complexities of Sex Determination Y-STR and Paternal Ancestry Mitochondrial STRs Forensic Serology: Whose Blood Is This? Is It Human? How to Extract DNA from a Biological Sample at a Crime Scene A Simple Guide for Understanding the Value of DNA Results: A Short Discussion on Probability and Statistical Calculations What Are Autosomal Dominant, Recessive, and X-Linked Dominant and Recessive Traits?
